ALL -- Acute Lymphocytic Leukemia -- What is it?
Acute lymphocytic leukemia (ALL) results from an acquired (not
inherited) genetic injury to the DNA of a single cell in the bone
marrow. The disease is often referred to as acute lymphoblastic
leukemia because the leukemic cell that replaces the normal marrow
is the (leukemic) lymphoblast. The effects are: 1) the uncontrolled
and exaggerated growth and accumulation of cells called "lymphoblasts"
or "leukemic blasts " which fail to function as normal
blood cells and 2) the blockade of the production of normal marrow
cells, leading to a deficiency of red cells (anemia), platelets
(thrombocytopenia), and normal white cells (especially neutrophils,
i.e., neutropenia) in the blood.
Symptoms
You might see the following symtoms:
- Shortness of Breath
- Fatigue (Feeling Sleepy or Tired)
- Bruise easily
- Cuts heal very slowly or you bleed easily
- Repeated infections
- Joint Pain
- Mild fevers
How do you diagnose AML?
You diagnose this with a blood test. The cells need to be examined
under a microscope to see if they are the correct type.
